Cost-Effectiveness of Treating Upper Limb Spasticity Due to Stroke with Botulinum Toxin Type A: Results from the Botulinum Toxin for the Upper Limb after Stroke (BoTULS) Trial
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چکیده
منابع مشابه
Cost-Effectiveness of Treating Upper Limb Spasticity Due to Stroke with Botulinum Toxin Type A: Results from the Botulinum Toxin for the Upper Limb after Stroke (BoTULS) Trial
Stroke imposes significant burdens on health services and society, and as such there is a growing need to assess the cost-effectiveness of stroke treatment to ensure maximum benefit is derived from limited resources. This study compared the cost-effectiveness of treating post-stroke upper limb spasticity with botulinum toxin type A plus an upper limb therapy programme against the therapy progra...
متن کاملBoTULS: a multicentre randomised controlled trial to evaluate the clinical effectiveness and cost-effectiveness of treating upper limb spasticity due to stroke with botulinum toxin type A.
OBJECTIVE To compare the clinical effectiveness and cost-effectiveness of treating upper limb spasticity due to stroke with botulinum toxin type A plus an upper limb therapy programme with the upper limb therapy programme alone. DESIGN A multicentre open-label parallel-group randomised controlled trial and economic evaluation. SETTING Twelve stroke services in the north of England, UK. PA...
متن کاملcomparing the efficacy of botulinum toxin with tizanidine in upper limb post stroke spasticity.
background: this study evaluated the efficacy of focal intramuscular injection of botulinum (bont) toxin type a in comparison with oral tizanidine (tzd) in treatment of post-stroke upper limb spasticity. methods: this was a double-blinded randomized clinical trial that recruited 68 patients with post-stroke upper limb spasticity. thirty-four patients received bont (dysport(®)) injections in aff...
متن کاملRepeated dosing of botulinum toxin type A for upper limb spasticity following stroke.
The authors evaluated the long-term efficacy and safety of botulinum toxin type A (BTX-A) in poststroke spasticity patients who completed a 12-week placebo-controlled study and received multiple open-label treatments with 200 to 240 U BTX-A for 42 weeks. Significant and sustained improvements were observed for Disability Assessment and Ashworth scores. Adverse events were generally mild. This e...
متن کاملInvestigating muscle selection for botulinum toxin-A injections in adults with post-stroke upper limb spasticity.
BACKGROUND Limited empirical information exists regarding botulinum toxin-A injector decision-making practices for adult upper limb post-stroke spasticity. The design of most studies prevents such an assessment, as injection sites and dosage are mandated by researcher protocols. This contrasts to usual injector practices, where individualized decision-making is the standard of care. DESIGN Se...
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ژورنال
عنوان ژورنال: Toxins
سال: 2012
ISSN: 2072-6651
DOI: 10.3390/toxins4121415